Proton Pump Inhibitors: More Indigestion than Relief?
نویسندگان
چکیده
Proton pump inhibitors (PPIs) are widely prescribed to treat a number of gastrointestinal (GI) disorders due to excessive acid production. While effective and safe, adverse renal effects have been increasingly described in epidemiological literature. The most well-documented adverse renal outcome is acute interstitial nephritis; however, association with overall acute kidney injury has also been recently reported. Recently, two observational studies have linked PPI use with chronic kidney disease. Finally, hypomagnesemia is another reported complication and is thought to be resulting from GI loss of magnesium. This study will critically review literature on the effect of PPIs on the kidney.
منابع مشابه
Division of Gastrointestinal and Coagulation Drug Products
PPI inhibitor; inhibitor of gastric acid secretion 20 mg tablets The sponsor proposes that one over-the-counter oral tablet be administered for the relief of heartburn, acid indigestion and sour stomach or for the prevention of these symptoms brought on by consuming food and beverages or associated with events such as stress, hectic life style, lying down for exercise, once every 24 hours for n...
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